The field of energy systems and industrial automation has seen significant advancements, driven by the increasing complexity and demands of modern industrial applications. This book offers a comprehensive understanding of real-time simulation methodologies and applications in these critical areas. Real-time simulation is crucial in academia and industry, particularly in electric power conversion and industrial processes. It enables safe product development and testing, efficiency improvements, and system reliability. Real-time simulations also support training, ensuring workers and students are prepared for real-world scenarios. This book bridges the gap between research and practical implementation, presenting foundational principles and cutting-edge techniques. Chapters cover dynamic system modeling, hardware-in-the-loop system development for industrial processes, power converters, regional integrated energy systems, and issues in interconnected simulation systems. This resource aims to advance knowledge and develop more efficient, reliable industrial systems, benefiting students, researchers, and professionals in power electronics, control systems, and industrial automation.