Changes in surfactant 17R4 concentration influenced the physio-chemical characteristics of an oil- in-water emulsion the most.From the study, we can conclude that the physcio-chemical properties of an oil-in-water emulsion were mostly affected by the variations in the contents of surfactant 17R4 A and NaCl. The NaCl-surfactant-oil interactions had a strong influence on the stability of the prepared emulsion. Pluronic surfactant 17R4 when used in minimal amount (1%) alongside Ludox and 2mg NaCl resulted to the most stable emulsion which stood on the bench beyond 6months without any sign of creaming. Oil-in-water emulsion wastes may be effectively treated using the electrochemical destabilization method. The aluminum provided and the bulk pH are the two most critical factors in the process. Experiments with a steady-state pH outside of the 5–9 range result in no emulsion break-up and, as a result, no COD elimination. In addition, the electrolyte has a significant impact on the outcomes. According to our second scheme, we found that nanoemulsion has the potentially help for enhancing the oral bioavailability of ibuprofen.