This study intends to identify the factors that influence knowledge sharing between individuals in the United Arab Emirates (UAE) context, specifically knowledge sharing from expatriates to UAE citizens, at both an individual and organizational level. This research aims to highlight the determinants of knowledge-sharing behaviors and the role of interpersonal relations (social trust) in the knowledge transfer process. These factors can subsequently be considered by organizations and human resource (HR) practitioners to facilitate the successful implementation of knowledge-sharing behavior and knowledge transfer in UAE organizations and support UAE’s Emiratization policies and processes. The results reveal that leader support for knowledge sharing as well as the incentive and reward system are effective factors to enhance individual knowledge sharing. Likewise, several individual-level factors were examined, and the results reveal that self-efficacy, mutual reciprocity, and altruism positively influence employee engagement in knowledge-sharing behavior at the workplace in a UAE context.