India has a rich flora that is widely distributed throughout the country. Plant derived drugs have been a part of the evolution of human healthcare for thousands of years. Many of the plants used today were known to the people of ancient cultures throughout the world & were extremely measured their preservative & medicinal powers. The tradition of medicinal plants to heal human diseases has extensive history with Ayurveda. In Ayurvedic medicine a particular plant otherwise combination of plants are used to treat a lot of diseases lacking of enough knowledge about particular target that is responsible for the causing disease & the mechanism of action of plant crudes. The traditional plants medicines are the treatment which was the resultant of the interaction of the human with the nature ,as they are living in the natures form the millions of the years, so they are aware from the all the uses of the nature & the plants. It have been the basis of treatment & cure for various diseases and physiological conditions in traditional methods practiced in India such as Ayurveda, Unani and Siddha.