Harmonious balance in health depends upon the quality of life (QOL). QOL is the condition of life resulting from the combination of the effects of the complete range of factors such as those determining health, happiness, education, social and intellectual attainments, freedom of action, justice and freedom of expression. This research aimed to assess the QOL of people affected with HIV/AIDS in Pakistan, as it has yet to be explored.This exploratory study by non-probability, convenient sampling was conducted on 139 selected HIV/AIDS positive and registered cases at the Voluntary Counseling Testing Centers (VCT centers) at Services and Jinnah hospitals Lahore, within 6 months in 2019. Data was collected using WHOQOL BREF Questionnaire. The SPSS software was used for data compilation and analysis. The investigator herself took the interviews, after an informed consent.A total of 139cases of HIV/AIDS positive registered individuals were taken. The mean age was 32.12 ± 8.54, with 78.4% males and 21.6% females. Quality of life (QOL) tables with domains were calculated; in the WHOQOL-BREF; higher score in the domains refers to good QOL.