Aluminum is very predominant metals with different alloying elements like: magnesia, silicon, tin, copper, magnesium and zinc. Important discussion for the field of metallurgy and engineering due to having fabrication & formability for the different products. In the world of precision TIG welding provides the best and suitable processes used in nuclear industries, automobile industries, aerospace industries and marine industries. In this book, we used the details of TIG welding on the different samples 2mm, 3mm and 5 mm thickness on 5052 aluminum alloy plate.Welding speed, gas flow rate & welding current are the final governing parameters in this book. Also, the output parameters after several readings on the taken sets of specimen are studied and various optimized step by using RSM (Response Surface Methodology), And MINI TAB Software taken for the better quality of welded joints and their strength of weld. Tensile strength and hardness of weld joint will analyze over the specimen through the optical microscope and UTM.