Pollinosis is on the rise worldwide, especially among children and adolescents. The paper elucidates the dependence of pollinosis spread on heredity, lifestyle and anthropogenic load. Two groups of teenagers of 16 years old (52 - in an industrial metropolis and 47 - in an urban-type working settlement) were studied. It is established that the incidence of pollinosis in adolescents is significantly higher in the industrial metropolis and depends to the greatest extent on heredity, as well as on lifestyle, in particular, on living conditions, nutrition, and whether the teenager is engaged in sports. The book will be useful to a wide range of readers interested in etiology, pathogenesis and pollinosis prevention.