The aim of this book is to provide a brief work contain synthesis, characteristics, antimicrobial and anti-tuber studies of novel pyrazole and pyridine heterocyclic compounds..They have been utilized for cultural and medicinal applications. Penicillinis splendid innovation and due to its prominent bactericidal properties, it acts as a one of the most demanding research focus on heterocyclic chemistry in chemical as well as pharma industries in the form of different active agents and number of biological receptor. Synthetic heterocyclic compounds have multiple applications in the area of medicines and agriculture field. This study is carried out Mr. Mayursinh Zala, Department of Chemistry C. U. Shah University, Wadhwan City, INDIA We hope the readers can enjoy this text and find it useful in their respective studies.