The definition of PCOS has led to an impressive increase of scientific interest in this disorder, which should be further directed to improve individualized clinical approaches and consequently therapeutic strategies. In this book, the most relevant and recent reports related to PCOS are described, also author has briefly addressed the pathophysiology of the disease, and dwelt in more depth into its diagnostic criteria. Throughout the literature, author has described complexity of PCOS in terms of introduction of PCOS, worldwide prevalence of PCOS, pathophysiology, diagnosis, morbidities, and the appropriate gentle treatment approach it requires. This special issue aims to publish groundbreaking researches that may open new scenarios and change the perspective of the topic. "Homeopathy works at its best in PCOS cases"!