This Text book introduces the theoretical formulation of AIS-MACA (Artificial Immune System based Multiple Attractor Cellular Automata) and its design goals. In this book an efficient implementation of the proposed classifier with modified CLONAL algorithm is presented. The various phases in modified CLONAL algorithm like random generation of the initial population, selection, cloning and mutation are demonstrated with algorithms and appropriate examples. The working of AIS-MACA was explained with an examples.