Efficacy of cefuroxime and ampicillin-sulbactam in surgery

Increasing global emergence of antimicrobial resistance and the transition to the era of managed care requiring specific clean surgical procedures with cost containment and quality assurance are the two main factors which highlight the need to optimize the use of prophylactic antibiotic in surgery. Surgeons encounter a wide range of infectious conditions including established single pathogens infection at soft tissue, poly-microbial intra-abdominal infections, and resistant nosocomial infections such as ventilator associated or aspiration pneumonias.